Incidence and prognostic relevance of supraventricular arrhythmias were evaluated in nine studies.These studies investigated patients with different forms of pulmonary hypertension.Supraventricular arrhythmias were more often found in patients with group two pulmonary hypertension.Common findings in these patients were elevated right atrial pressur
In complement to an effective vaccine, development of potent anti-HIV microbicides remains an important priority.We have previously shown that the miniCD4 M48U1, a functional mimetic of sCD4 presented on a 27 amino-acid stable scaffold, inhibits a broad range of HIV-1 isolates at sub-nanomolar concentrations in cellular models.Here, we report that
Undifferentiated carcinoma of the pancreas (UDC) is rare and has a dismal prognosis.Here, we report a case of 6-year disease-free survival with a mixed bostik mvp type of UDC and UDC with osteoclast-like giant cells, with a high mitotic index as well as perineural, lymphatic, vessel, and diaphragmatic invasion.The patient underwent radical distal p
Since their identification over twenty-five years ago, the plethora of cell-penetrating peptides (CPP) and their applications has skyrocketed.These 5 to 30 amino acid in length peptides have the unique property of breaching the cell taylor te400 membrane barrier while carrying cargoes larger than themselves into cells in an intact, functional form.
BACKGROUND:Primaquine is the only licensed antimalarial for the radical cure of Plasmodium vivax infections.Many countries, however, do not administer primaquine due to fear of hemolysis in those with glucose-6-phosphate dehydrogenase (G6PD) deficiency.In other settings, primaquine is given without G6PD testing, putting patients at risk of hemolysi